Quinone Reductase 1 (NQO1) Antikörper (Cy5)

Antigen: Quinone Reductase 1 (NQO1)

Synonyme: DTD, QR1, DHQU, DIA4, NMOR1, NMORI, Dtd, Ox1, Qr1, Dia4, Nmo1, Ox-1, Nmo-1, Nmor1, AV001255, MGC93075

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus, Ratte (Rattus), Meerschweinchen, Schwein, Kaninchen, Pferd

Konjugat: Cy5

Applikation: Durchflusszytometrie (FACS), Immunfluoreszenz (IF)

Produktnummer: ABIN678432

Produktbeschreibung

Weitere Bezeichnung: NQO1

Immunogen: Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human NQO1 C-terminus

Format: Lyophilized

Wiederherstellung: Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%)

Isotyp: IgG

Beschreibung: Synonym: NAD(P)H:quinone oxidoreductase l, Azoreductase, Cytochrome b 5 reductase, DHQU, DIA 4, DIA4, Diaphorase (NADH/NADPH) (cytochrome b-5 reductase), Diaphorase (NADH/NADPH), Diaphorase 4, Dioxin inducible 1, DT diaphorase, DTD, Menadione reductase, NAD(P)H dehydrogenase quinone 1, NAD(P)H menadione oxidoreductase 1 dioxin inducible, NAD(P)H: menadione oxidoreductase 1 dioxin inducible 1, NAD(P)H:menadione oxidoreductase 1, NAD(P)H:Quinone acceptor oxidoreductase type 1, NAD(P)H:quinone oxidoreductase 1, NAD(P)H:quinone oxireductase, NMOR 1, NMOR I, NMOR1, NMORI, NQO 1, Phylloquinone reductase, QR 1, QR1, Quinone reductase 1.

Spezifität: Excitation / Emission Wavelengths: 650nm/670nm

Molekulargewicht: 30kDa

Kommentare:

This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD)

an increased risk of hematotoxicity after exposure to benzene

and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants

encoding different isoforms

have been characterized. [provided by RefSeq].

Anwendungen

Applikationshinweise: Flow-Cyt (1:50-200), IF (1:50-200)

Konzentration: 1mg/1ml

Reinigung: Antibodies are purified by protein A and peptide affinity chromatography.

Buffer: 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

Lagerung: Ship at room temperature. Store at -20°C

Beschränkungen: Nur für Forschungszwecke einsetzbar