ABCB6 Antikörper (AA 401-520) (Biotin)

Produktnummer ABIN673616

Der Kaninchen Polyklonal anti-ABCB6 Antikörper wird verwendet zum Nachweis von ABCB6 in Proben von Human, Maus und Ratte. Er wurde validiert für ELISA, IHC (p) und IHC (fro).

Kurzübersicht für ABCB6 Antikörper (AA 401-520) (Biotin) (ABIN673616)

Target: ABCB6 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 (ABCB6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABCB6 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-ABCB6 Antikörper (Biotin)

Bindungsspezifität: AA 401-520

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Horse,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ABCB6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu ABCB6

Target: ABCB6 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 (ABCB6))

Andere Bezeichnung: ABCB6

Hintergrund:

Synonyms: ABC, ABC14, EST45597, ABC 14, ABC-14, ABCB 6, ABCB-6, PRP, UMAT, ABC transporter umat, MTABC3, Mt-ABC transporter 3, umat, Mitochondrial precursor, Mitochondrial ABC transporter 3, Mitochondrial abc protein 3, ATP-binding cassette, sub-family B, member 6, mitochondrial precursor, ATP binding cassette, sub family B MDR/TAP, member 6, P glycoprotein related protein, Abcb6, ABCB6_HUMAN, ATP binding cassette sub family B member 6, mitochondrial precursor, ATP-binding cassette sub-family B member 6, Mitochondrial ABC transporter 3, mitochondrial, Mt ABC transporter 3, P-glycoprotein-related protein, Ubiquitously-expressed mammalian ABC half transporter, UMAT, Ubiquitously expressed mammalian ABC half transporter.

Background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.

Gen-ID: 10058

Pathways: Transition Metal Ion Homeostasis