BEAN1 Antikörper (N-Term)

Produktnummer ABIN657309

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-BEAN1 Antikörper (Klon RB32748) (ABIN657309) detektiert spezifisch BEAN1 in WB und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für BEAN1 Antikörper (N-Term) (ABIN657309)

Target: BEAN1 (Brain Expressed, Associated with NEDD4, 1 (BEAN1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BEAN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB32748

Produktdetails anti-BEAN1 Antikörper

Bindungsspezifität: AA 45-73, N-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This BEAN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-73 amino acids from the N-terminal region of human BEAN.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-BEAN1 Antikörper (ABIN657309)

Shapaer, Chen, Pan, Wu, Tang, Zhao, Zeng: "Elevated BEAN1 expression correlates with poor prognosis, immune evasion, and chemotherapy resistance in rectal adenocarcinoma." in: Discover oncology, Vol. 15, Issue 1, pp. 446, (2024) (PubMed).

Details zu BEAN1

Target: BEAN1 (Brain Expressed, Associated with NEDD4, 1 (BEAN1))

Andere Bezeichnung: BEAN

Hintergrund: The protein encoded by this gene is one of several proteins that interact with NEDD4, a member of a family of ubiquitin-protein ligases. These proteins have PY motifs in common that bind to the WW domains of NEDD4. NEDD4 is developmentally regulated, and is highly expressed in embryonic tissues. Mutations in this gene (i.e., intronic insertions of >100 copies of pentanucleotide repeats including a (TGGAA)n sequence) are associated with spinocerebellar ataxia type 31. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 28626

NCBI Accession: NP_001129578, NP_001171491, NP_001184154

UniProt: Q3B7T3