CLCN7 Antikörper (C-Term)

Produktnummer ABIN655808

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-CLCN7 Antikörper wird verwendet zum Nachweis von CLCN7 in Proben von Human. Er wurde validiert für WB, IF und IHC (p).

Kurzübersicht für CLCN7 Antikörper (C-Term) (ABIN655808)

Target: CLCN7 (Chloride Channel, Voltage-Sensitive 7 (CLCN7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLCN7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB31756

Produktdetails anti-CLCN7 Antikörper

Bindungsspezifität: AA 692-720, C-Term

Homologie: B, M, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CLCN7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 692-720 amino acids from the C-terminal region of human CLCN7.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-CLCN7 Antikörper (ABIN655808)

Yoshimoto, Morita, Matsubara, Mitsuyasu, Imai, Kajioka, Yoneda, Ito, Hirofuji, Nakamura, Hirata: "Surface vacuolar ATPase in ameloblastoma contributes to tumor invasion of the jaw bone." in: International journal of oncology, Vol. 48, Issue 3, pp. 1258-70, (2016) (PubMed).

Details zu CLCN7

Target: CLCN7 (Chloride Channel, Voltage-Sensitive 7 (CLCN7))

Andere Bezeichnung: CLCN7

Hintergrund: The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood.

Molekulargewicht: 88679

Gen-ID: 1186

NCBI Accession: NP_001107803, NP_001278

UniProt: P51798