ADH4 Antikörper (C-Term)

Produktnummer ABIN654087

Zitiert in 2+ Publikationen. Der Kaninchen Polyklonal anti-ADH4 Antikörper (Klon RB21606) (ABIN654087) detektiert spezifisch ADH4 in WB, FACS und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für ADH4 Antikörper (C-Term) (ABIN654087)

Target: ADH4 (Alcohol Dehydrogenase 4 (Class II), pi Polypeptide (ADH4))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADH4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB21606

Produktdetails anti-ADH4 Antikörper

Bindungsspezifität: AA 319-348, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ADH4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 319-348 amino acids from the C-terminal region of human ADH4.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-ADH4 Antikörper (ABIN654087)

Attignon, Leblanc, Le-Grand, Duval, Aggerbeck, Rouach, Blanc: "Novel roles for AhR and ARNT in the regulation of alcohol dehydrogenases in human hepatic cells." in: Archives of toxicology, Vol. 91, Issue 1, pp. 313-324, (2017) (PubMed).

Renon, Legrand, Blanc, Daubigney, Bokobza, Mortreux, Paul, Delabar, Rouach, Andreau, Janel: "Impact of Dyrk1A level on alcohol metabolism." in: Biochimica et biophysica acta, Vol. 1862, Issue 9, pp. 1495-503, (2016) (PubMed).

Details zu ADH4

Target: ADH4 (Alcohol Dehydrogenase 4 (Class II), pi Polypeptide (ADH4))

Andere Bezeichnung: ADH4

Hintergrund: This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes.

Molekulargewicht: 40222

Gen-ID: 127

NCBI Accession: NP_000661

UniProt: P08319

Pathways: Transition Metal Ion Homeostasis