Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ID4 in WB, IHC, FACS und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human und Maus.
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This ID4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human ID4.
ID4
Reaktivität: Human
ELISA, IF
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
FC: 1:10~50. WB: 1:1000. IHC-P: 1:50~100
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Target
ID4
(Inhibitor of DNA Binding 4, Dominant Negative Helix-Loop-Helix Protein (ID4))
Andere Bezeichnung
ID4
Hintergrund
ID4 is transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number of mammalian and insect systems. DNA-binding activity of the bHLH proteins is dependent on formation of homo- and/or heterodimers. Dominant-negative HLH proteins encoded by Id-related genes, such as ID4, also contain the HLH-dimerization domain but lack the DNA-binding basic domain. Consequently, Id proteins inhibit binding to DNA and transcriptional transactivation by heterodimerization with bHLH proteins