ATP6V1A Antikörper (AA 441-468)

Produktnummer ABIN653735

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-ATP6V1A Antikörper wird verwendet zum Nachweis von ATP6V1A in Proben von Human. Er wurde validiert für WB und IHC (p).

Kurzübersicht für ATP6V1A Antikörper (AA 441-468) (ABIN653735)

Target: ATP6V1A (ATPase, H+ Transporting, Lysosomal 70kDa, V1 Subunit A (ATP6V1A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP6V1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB24578

Produktdetails anti-ATP6V1A Antikörper

Bindungsspezifität: AA 441-468

Homologie: B, M, Pig

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ATP6V1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 441-468 amino acids from the Central region of human ATP6V1A.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-ATP6V1A Antikörper (ABIN653735)

Nabatov, Hatzis, Rouschop, van Diest, Vooijs: "Hypoxia inducible NOD2 interacts with 3-O-sulfogalactoceramide and regulates vesicular homeostasis." in: Biochimica et biophysica acta, Vol. 1830, Issue 11, pp. 5277-86, (2013) (PubMed).

Details zu ATP6V1A

Target: ATP6V1A (ATPase, H+ Transporting, Lysosomal 70kDa, V1 Subunit A (ATP6V1A))

Andere Bezeichnung: ATP6V1A

Hintergrund: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain A subunit isoforms and is found in all tissues.

Molekulargewicht: 68304

Gen-ID: 523

NCBI Accession: NP_001681

UniProt: P38606

Pathways: Transition Metal Ion Homeostasis, Proton Transport, SARS-CoV-2 Protein Interaktom