PDE6C Antikörper (AA 271-300)

Produktnummer ABIN653683

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PDE6C in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human und Maus.Es wurde in 1 Publikation zitiert.

Kurzübersicht für PDE6C Antikörper (AA 271-300) (ABIN653683)

Target: PDE6C (phosphodiesterase 6C, CGMP-Specific, Cone, alpha Prime (PDE6C))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE6C Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB24356

Produktdetails anti-PDE6C Antikörper

Bindungsspezifität: AA 271-300

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PDE6C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 271-300 amino acids from the Central region of human PDE6C.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-PDE6C Antikörper (ABIN653683)

Xu, Morris, Thapa, Ma, Michalakis, Biel, Baehr, Peshenko, Dizhoor, Ding: "cGMP accumulation causes photoreceptor degeneration in CNG channel deficiency: evidence of cGMP cytotoxicity independently of enhanced CNG channel function." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 37, pp. 14939-48, (2013) (PubMed).

Details zu PDE6C

Target: PDE6C (phosphodiesterase 6C, CGMP-Specific, Cone, alpha Prime (PDE6C))

Andere Bezeichnung: PDE6C

Hintergrund: PDE6C is the alpha-prime subunit of cone phosphodiesterase, which is composed of a homodimer of two alpha-prime subunits and 3 smaller proteins of 11, 13, and 15 kDa.

Molekulargewicht: 99147

Gen-ID: 5146

NCBI Accession: NP_006195

UniProt: P51160