BDK_1 (AA 213-239) Antikörper

Produktnummer ABIN652683

Der Kaninchen Polyklonal anti-BDK_1 Antikörper (Klon RB21729) (ABIN652683) detektiert spezifisch BDK_1 in FACS und WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für BDK_1 (AA 213-239) Antikörper (ABIN652683)

Target: BDK_1

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Applikation: Flow Cytometry (FACS), Western Blotting (WB)

Klon: RB21729

Produktdetails

Bindungsspezifität: AA 213-239

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This BDK_1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-239 amino acids from the Central region of human BDK_1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Antigendetails

Target: BDK_1

Hintergrund: Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. BDKRB1 is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses.

Molekulargewicht: 40495

Gen-ID: 623

NCBI Accession: NP_000701

UniProt: P46663