Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch YME1L1 in WB, FACS und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human und Hamster.Es wurde in 1 Publikation zitiert.
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This YMEL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-219 amino acids from the N-terminal region of human YMEL1.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Parajuli, Shrum, Tobacyk, Harb, Arthur, MacMillan-Crow: "Renal cold storage followed by transplantation impairs expression of key mitochondrial fission and fusion proteins." in: PLoS ONE, Vol. 12, Issue 10, pp. e0185542, (2017) (PubMed).
Target
YME1L1
(YME1-Like 1 (YME1L1))
Andere Bezeichnung
YMEL1
Hintergrund
YMEL1 is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies.