ILK Antikörper (pSer343)

Produktnummer ABIN650820

Zitiert in 2+ Publikationen. Der Kaninchen Polyklonal anti-ILK Antikörper (Klon RB13896) (ABIN650820) detektiert spezifisch ILK in DB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für ILK Antikörper (pSer343) (ABIN650820)

Target: ILK (Integrin-Linked Kinase (ILK))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ILK Antikörper ist unkonjugiert

Applikation: Dot Blot (DB)

Klon: RB13896

Produktdetails anti-ILK Antikörper

Bindungsspezifität: pSer343

Homologie: B, M, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ILK Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S343 of human ILK.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: DB: 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-ILK Antikörper (ABIN650820)

Brooker, Bond, Peng, Kessler: "β1-integrin restricts astrocytic differentiation of adult hippocampal neural stem cells." in: Glia, Vol. 64, Issue 7, pp. 1235-51, (2018) (PubMed).

Srikanth, Das, Berns, Kim, Stupp, Kessler: "Nanofiber-mediated inhibition of focal adhesion kinase sensitizes glioma stemlike cells to epidermal growth factor receptor inhibition." in: Neuro-oncology, Vol. 15, Issue 3, pp. 319-29, (2013) (PubMed).

Details zu ILK

Target: ILK (Integrin-Linked Kinase (ILK))

Andere Bezeichnung: ILK

Hintergrund: Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. ILK is a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction.

Molekulargewicht: 51419

Gen-ID: 3611

NCBI Accession: NP_001014794, NP_001014795, NP_001265370, NP_004508

UniProt: Q13418

Pathways: Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration