H2AFY2 Antikörper (Middle Region)
Kurzübersicht für H2AFY2 Antikörper (Middle Region) (ABIN630681)
Target
Alle H2AFY2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Spezifität
- H2 AFY2 antibody was raised against the middle region of H2 FY2
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Aufreinigung
- Affinity purified
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Immunogen
- H2 AFY2 antibody was raised using the middle region of H2 FY2 corresponding to a region with amino acids PRIHPELLAKKRGTKGKSETILSPPPEKRGRKATSGKKGGKKSKAAKPRT
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Applikationshinweise
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
Kommentare
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H2AFY2 Blocking Peptide, (ABIN5613918), is also available for use as a blocking control in assays to test for specificity of this H2AFY2 antibody
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of H0 FY2 antibody in PBS
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Konzentration
- Lot specific
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Buffer
- PBS
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Handhabung
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- H2AFY2 (H2A Histone Family, Member Y2 (H2AFY2))
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Andere Bezeichnung
- H2AFY2
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Hintergrund
- H2AFY2 is the variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. H2AFY2 may be involved in stable X chromosome inactivation.
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Molekulargewicht
- 40 kDa (MW of target protein)
Target
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