SERPINB6 Antikörper (Middle Region)
Kurzübersicht für SERPINB6 Antikörper (Middle Region) (ABIN567507)
Target
Alle SERPINB6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- LVLVNAVYFR GNWDEQFDKE NTEERLFKVS KNEEKPVQMM FKQSTFKKTY
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Homologie
- Cow: 79%, Human: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against SERPINB6. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human SERPINB6
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 376 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SERPINB6 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 6 (SERPINB6))
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Andere Bezeichnung
- SERPINB6
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Hintergrund
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The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene.
Alias Symbols: CAP, DKFZp686I04222, MGC111370, MSTP057, PI6, PTI, SPI3, DFNB91
Protein Interaction Partner: SUMO2, C16orf70, AHCY, CRK, UBC, F10, PLAU, F2, PROC, PLG, KLK2,
Protein Size: 376 -
Molekulargewicht
- 41 kDa
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Gen-ID
- 5269
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NCBI Accession
- NM_004568, NP_004559
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UniProt
- P35237
Target
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