KHDRBS2 Antikörper (N-Term)

Produktnummer ABIN567276

Der Kaninchen Polyklonal anti-KHDRBS2 Antikörper (ABIN567276) detektiert spezifisch KHDRBS2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd und Kaninchen.

Kurzübersicht für KHDRBS2 Antikörper (N-Term) (ABIN567276)

Target: KHDRBS2 (KH Domain Containing, RNA Binding, Signal Transduction Associated 2 (KHDRBS2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KHDRBS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-KHDRBS2 Antikörper

Bindungsspezifität: N-Term

Sequenz: EEIEKFQGSD GKKEDEEKKY LDVISNKNIK LSERVLIPVK QYPKFNFVGK

Homologie: Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against KHDRBS2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KHDRBS2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 349 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu KHDRBS2

Target: KHDRBS2 (KH Domain Containing, RNA Binding, Signal Transduction Associated 2 (KHDRBS2))

Andere Bezeichnung: KHDRBS2

Hintergrund: KHDRBS2 is a RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. KHDRBS2 induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. KHDRBS2 may function as an adapter protein for Src kinases during mitosis. KHDRBS2 binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability.
Alias Symbols: FLJ38664, MGC26664, SLM-1, SLM1, bA535F17.1
Protein Interaction Partner: HBZ, DOCK2, CIRBP, TYMSOS, LINC01018, KHDRBS2, ZFC3H1, CATSPER1, YTHDC1, PRR3, NABP1, AEN, NCOA5, NPDC1, RBMX, PRPF31, CHTOP, HNRNPR, MTA1, TYK2, SULT1A3, SPG7, SDCBP, RBM3, PTK6, UBC, KHDRBS3, HNRNPK, LYN, HNRNPC, HNRNPA2B1, HNRNPA1, FGG, FGB, FGA, DSG1,
Protein Size: 349

Molekulargewicht: 39 kDa

Gen-ID: 202559

NCBI Accession: NM_152688, NP_689901

UniProt: Q5VWX1