HNRNPU Antikörper (C-Term)

Produktnummer ABIN567136

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HNRNPU in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen und Pferd.

Kurzübersicht für HNRNPU Antikörper (C-Term) (ABIN567136)

Target: HNRNPU (Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HNRNPU Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HNRNPU Antikörper

Bindungsspezifität: C-Term

Sequenz: EITYVELQKE EAQKLLEQYK EESKKALPPE KKQNTGSKKS NKNKSGKNQF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HNRNPU. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HNRNPU

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 825 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HNRNPU

Target: HNRNPU (Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU))

Andere Bezeichnung: HNRNPU

Hintergrund: HNRNPU belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. HNRNPU contains a RNA binding domain and scaffold-associated region (SAR)-specific bipartite DNA-binding domain. This protein is also thought to be involved in the packaging of hnRNA into large ribonucleoprotein complexes. During apoptosis, this protein is cleaved in a caspase-dependent way. But this cleavage does not affect the function of the encoded protein in RNA metabolism.
Alias Symbols: HNRPU, SAF-A, U21.1, hnRNP U
Protein Interaction Partner: FBXW11, FUS, HUWE1, BTRC, UBC, TUBG1, TP53, AURKA, MAGED2, TUBGCP3, CEP57, AURKB, SUMO2, SUMO3, CEP70, CEP76, MDM2, LGALS3BP, EMD, HAUS2, TUBGCP4, CEP250, NEDD1, STAU1, IVNS1ABP, LGR4, ERG, RPA3, RPA2, RPA1, WWOX, RNF2, SHFM1, EED, rev, RPS29, RPS27, RPS6
Protein Size: 825

Molekulargewicht: 90 kDa

Gen-ID: 3192

NCBI Accession: NM_031844, NP_114032

UniProt: Q00839