Coronin 1a Antikörper (AA 360-461)

Produktnummer ABIN564843

Zitiert in 3+ Publikationen. Der Maus Monoklonal anti-Coronin 1a Antikörper (Klon 4G10) (ABIN564843) detektiert spezifisch Coronin 1a in WB, ELISA und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Coronin 1a Antikörper (AA 360-461) (ABIN564843)

Target: Coronin 1a (CORO1A) (Coronin, Actin Binding Protein, 1A (CORO1A))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Coronin 1a Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 4G10

Produktdetails anti-Coronin 1a Antikörper

Bindungsspezifität: AA 360-461

Verwendungszweck: Mouse monoclonal antibody raised against a partial recombinant CORO1A.

Sequenz: QEDLYPPTAG PDPALTAEEW LGGRDAGPLL ISLKDGYVPP KSRELRVNRG LDTGRRRAAP EASGTPSSDA VSRLEEEMRK LQATVQELQK RLDRLEETVQ AK

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: CORO1A (NP_009005, 360 a.a. ~ 461 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-Coronin 1a Antikörper (ABIN564843)

Jayachandran, Liu, Bosedasgupta, Müller, Zhang, Moshous, Studer, Schneider, Genoud, Fossoud, Gambino, Khelfaoui, Müller, Bartholdi, Rossez, Stiess, Houbaert, Jaussi, Frey, Kammerer, Deupi et al.: "Coronin 1 regulates cognition and behavior through modulation of cAMP/protein kinase A signaling. ..." in: PLoS biology, Vol. 12, Issue 3, pp. e1001820, (2014) (PubMed).

Federzoni, Humbert, Valk, Behre, Leibundgut, Torbett, Fey, Tschan: "The actin-binding protein CORO1A is a novel PU.1 (SPI1)- and CEBPA-regulated gene with significantly lower expression in APL and CEBPA-mutated AML patients." in: British journal of haematology, Vol. 160, Issue 6, pp. 855-9, (2013) (PubMed).

Moriceau, Kantari, Mocek, Davezac, Gabillet, Guerrera, Brouillard, Tondelier, Sermet-Gaudelus, Danel, Lenoir, Daniel, Edelman, Witko-Sarsat: "Coronin-1 is associated with neutrophil survival and is cleaved during apoptosis: potential implication in neutrophils from cystic fibrosis patients." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 11, pp. 7254-63, (2009) (PubMed).

Details zu Coronin 1a

Target: Coronin 1a (CORO1A) (Coronin, Actin Binding Protein, 1A (CORO1A))

Andere Bezeichnung: CORO1A

Hintergrund: Full Gene Name: coronin, actin binding protein, 1A
Synonyms: CLABP,CLIPINA,FLJ41407,HCORO1,MGC117380,TACO,p57

Gen-ID: 11151

NCBI Accession: NM_007074

Pathways: Regulation of Actin Filament Polymerization