HSD3B1 Antikörper (AA 1-373)

Produktnummer ABIN561369

Zitiert in 6+ Publikationen. Der Maus Monoklonal anti-HSD3B1 Antikörper (Klon 3C11-D4) (ABIN561369) detektiert spezifisch HSD3B1 in WB, ELISA und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für HSD3B1 Antikörper (AA 1-373) (ABIN561369)

Target: HSD3B1 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 1 (HSD3B1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HSD3B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 3C11-D4

Produktdetails anti-HSD3B1 Antikörper

Bindungsspezifität: AA 1-373

Verwendungszweck: Mouse monoclonal antibody raised against a full length recombinant HSD3B1.

Sequenz: MTGWSCLVTG AGGFLGQRII RLLVKEKELK EIRVLDKAFG PELREEFSKL QNKTKLTVLE GDILDEPFLK RACQDVSVII HTACIIDVFG VTHRESIMNV NVKGTQLLLE ACVQASVPVF IYTSSIEVAG PNSYKEIIQN GHEEEPLENT WPAPYPHSKK LAEKAVLAAN GWNLKNGGTL YTCALRPMYI YGEGSRFLSA SINEALNNNG ILSSVGKFST VNPVYVGNVA WAHILALRAL QDPKKAPSIR GQFYYISDDT PHQSYDNLNY TLSKEFGLRL DSRWSFPLSL MYWIGFLLEI VSFLLRPIYT YRPPFNRHIV TLSNSVFTFS YKKAQRDLAY KPLYSWEEAK QKTVEWVGSL VDRHKENLKS KTQ

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: HSD3B1 (AAH31999.1, 1 a.a. ~ 373 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-HSD3B1 Antikörper (ABIN561369)

Kubota-Nakayama, Nakamura, Konosu-Fukaya, Azmahani, Ise, Yamazaki, Kitawaki, Felizola, Ono, Omata, Morimoto, Iwama, Satoh, Sasano et al.: "Expression of steroidogenic enzymes and their transcription factors in cortisol-producing adrenocortical adenomas: immunohistochemical analysis and quantitative real-time polymerase chain reaction ..." in: Human pathology, Vol. 54, pp. 165-73, (2016) (PubMed).

Azmahani, Nakamura, Felizola, Ozawa, Ise, Inoue, McNamara, Doi, Okamura, Zouboulis, Aiba, Sasano: "Steroidogenic enzymes, their related transcription factors and nuclear receptors in human sebaceous glands under normal and pathological conditions." in: The Journal of steroid biochemistry and molecular biology, Vol. 144 Pt B, pp. 268-79, (2014) (PubMed).

Mao, Shih: "Advances in the diagnosis of gestational trophoblastic tumors and tumor-like lesions." in: Expert opinion on medical diagnostics, Vol. 3, Issue 4, pp. 371-80, (2013) (PubMed).

Ariel, Boldes, Weintraub, Reinus, Beller, Arbel: "Chorangiocarcinoma: a case report and review of the literature." in: International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists, Vol. 28, Issue 3, pp. 267-71, (2009) (PubMed).

Mao, Kurman, Jeng, Huang, Shih: "HSD3B1 as a novel trophoblast-associated marker that assists in the differential diagnosis of trophoblastic tumors and tumorlike lesions." in: The American journal of surgical pathology, Vol. 32, Issue 2, pp. 236-42, (2008) (PubMed).

Shih: "Trophogram, an immunohistochemistry-based algorithmic approach, in the differential diagnosis of trophoblastic tumors and tumorlike lesions." in: Annals of diagnostic pathology, Vol. 11, Issue 3, pp. 228-34, (2007) (PubMed).

Details zu HSD3B1

Target: HSD3B1 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 1 (HSD3B1))

Andere Bezeichnung: HSD3B1

Hintergrund: Full Gene Name: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
Synonyms: HSD3B,HSDB3,SDR11E1

Gen-ID: 3283

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Carbohydrate Homeostasis