PHLDA2 Antikörper (Middle Region)
Kurzübersicht für PHLDA2 Antikörper (Middle Region) (ABIN504439)
Target
Alle PHLDA2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- QNRRALQDFR SRQERTAPAA PAEDAVAAAA AAPSEPSEPS RPSPQPKPRT
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Homologie
- Human: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against PHLDA2. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PHLDA2
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 152 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "TSSC3 overexpression associates with growth inhibition, apoptosis induction and enhances chemotherapeutic effects in human osteosarcoma." in: Carcinogenesis, Vol. 33, Issue 1, pp. 30-40, (2011) (PubMed).
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- PHLDA2 (Pleckstrin Homology-Like Domain, Family A, Member 2 (PHLDA2))
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Andere Bezeichnung
- PHLDA2
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Hintergrund
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This gene is one of several genes in the imprinted gene domain of 11p15.5 which is considered to be an important tumor suppressor gene region. Alterations in this region may be associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma
Alias Symbols: BRW1C, BWR1C, HLDA2, IPL, TSSC3
Protein Interaction Partner: UBC,
Protein Size: 152 -
Molekulargewicht
- 17 kDa
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Gen-ID
- 7262
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NCBI Accession
- NM_003311, NP_003302
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UniProt
- Q53GA4
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Pathways
- Regulation of Carbohydrate Metabolic Process
Target
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