PCSK6 Antikörper (N-Term)

Produktnummer ABIN504370

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PCSK6 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Maus, Kaninchen, Hund, Rind (Kuh), Pferd, Meerschweinchen und Zebrafisch (Danio rerio).

Kurzübersicht für PCSK6 Antikörper (N-Term) (ABIN504370)

Target: PCSK6 (Proprotein Convertase Subtilisin/kexin Type 6 (PCSK6))

Reaktivität: Human, Ratte, Maus, Kaninchen, Hund, Rind (Kuh), Pferd, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCSK6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PCSK6 Antikörper

Bindungsspezifität: N-Term

Sequenz: NYDSYASYDV NGNDYDPSPR YDASNENKHG TRCAGEVAAS ANNSYCIVGI

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against PCSK6. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PCSK6

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 975 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PCSK6

Target: PCSK6 (Proprotein Convertase Subtilisin/kexin Type 6 (PCSK6))

Andere Bezeichnung: PCSK6

Hintergrund: PCSK6 is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. This gene is thought to play a role in tumor progression.The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: PACE4, SPC4
Protein Interaction Partner: env, UBC, CACNA1A, RCN3, FLG, PMCH, PCSK6,
Protein Size: 975

Molekulargewicht: 91 kDa

Gen-ID: 5046

NCBI Accession: NM_138320, NP_612193

UniProt: Q63415

Pathways: Neurotrophin Signalübertragung, SARS-CoV-2 Protein Interaktom