PAD4 Antikörper (Middle Region)

Produktnummer ABIN503594

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-PAD4 Antikörper wird verwendet zum Nachweis von PAD4 in Proben von Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein, Schaf und Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für PAD4 Antikörper (Middle Region) (ABIN503594)

Target: PAD4 (PADI4) (Peptidyl Arginine Deiminase, Type IV (PADI4))

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein, Schaf, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAD4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PAD4 Antikörper

Bindungsspezifität: Middle Region

Sequenz: TGGISGLDSF GNLEVSPPVT VRGKEYPLGR ILFGDSCYPS NDSRQMHQAL

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 87%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 86%, Rat: 100%, Sheep: 79%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against PADI4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PADI4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 663 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PAD4 Antikörper (ABIN503594)

Costenbader, Chang, De Vivo, Plenge, Karlson: "Genetic polymorphisms in PTPN22, PADI-4, and CTLA-4 and risk for rheumatoid arthritis in two longitudinal cohort studies: evidence of gene-environment interactions with heavy cigarette smoking." in: Arthritis research & therapy, Vol. 10, Issue 3, pp. R52, (2008) (PubMed).

Details zu PAD4

Target: PAD4 (PADI4) (Peptidyl Arginine Deiminase, Type IV (PADI4))

Andere Bezeichnung: PADI4

Hintergrund: PADI4 is an enzyme responsible for the conversion of arginine residues to citrulline residues. This protein may play a role in granulocyte and macrophage development leading to inflammation and immune response.This gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PAD, PADI5, PDI4, PDI5, PAD4
Protein Interaction Partner: ANXA4, FBXO25, APP, ING4, ELK1, NPM1, TP53, HDAC2, HIST2H3A, HDAC1, TFF1, HIST4H4, HIST3H3,
Protein Size: 663

Molekulargewicht: 74 kDa

Gen-ID: 23569

NCBI Accession: NM_012387, NP_036519

UniProt: Q9UM07