ZBED1 Antikörper (Center)

Produktnummer ABIN501137

Der Kaninchen Polyklonal anti-ZBED1 Antikörper wird verwendet zum Nachweis von ZBED1 in Proben von Human und Maus. Er wurde validiert für WB und EIA.

Kurzübersicht für ZBED1 Antikörper (Center) (ABIN501137)

Target: ZBED1 (Zinc Finger, BED-Type Containing 1 (ZBED1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZBED1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-ZBED1 Antikörper

Bindungsspezifität: Center

Spezifität: This antibody detects ZBED1. The antibody is predicted to have no cross-reactivity to ZBED2 or ZBED3.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse

Aufreinigung: Affinity chromatography

Immunogen: ZBED1 antibody was raised against a 15 amino acid peptide from near the center of human ZBED1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu ZBED1

Target: ZBED1 (Zinc Finger, BED-Type Containing 1 (ZBED1))

Andere Bezeichnung: ZBED1

Hintergrund: ZBED1, also known as DREF, is the human homolog of the Drosophila protein DREF, a transcriptional regulatory factor required for expression of genes involved in DNA replication and cell proliferation. RNA interference (RNAi) experiments targeting ZBED1 RNA resulted in the inhibition of S phase entry and reduction of histone H1 mRNA in HeLa cells, suggesting that ZBED1 also plays a role in cell proliferation in human cells. At least 22 ribosomal proteins (RPs) possess ZBED1 binding sites in their promoters, anti-ZBED1 RNAi also resulted in decreased RP gene expression. Immunoprecipitation analyses have shown that ZBED1 self-associates in vivo via a carboxyl-terminal hATC domain, and this self-association is required for nuclear localization and DNA binding.Synonyms: ALTE, DREF, KIAA0785, Putative Ac-like transposable element, Zinc finger BED domain-containing protein 1, dREF homolog

Gen-ID: 9189