PLIN3 Antikörper (C-Term)

Produktnummer ABIN500921

Der Kaninchen Polyklonal anti-PLIN3 Antikörper wird verwendet zum Nachweis von PLIN3 in Proben von Human und Ratte. Er wurde validiert für WB, IHC (p), IF und EIA.

Kurzübersicht für PLIN3 Antikörper (C-Term) (ABIN500921)

Target: PLIN3 (Perilipin 3 (PLIN3))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLIN3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-PLIN3 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects TIP47 / M6PRBP1 at C-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Rat

Aufreinigung: Peptide Affinity Chromatography

Immunogen: TIP47 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of Human TIP47.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PLIN3

Target: PLIN3 (Perilipin 3 (PLIN3))

Andere Bezeichnung: TIP47 / M6PRBP1

Hintergrund: Tail-interacting protein (TIP47) is a cytosolic protein essential for the transport of mannose-6-phosphate receptors (MPRs) from endosomes to the trans-Golgi compartments in cells. TIP47 is recruited from the cytoplasm to the late endosomal surface by the Ras-associated protein Rab9 GTPase, enabling it to bind more efficiently to MPR cytoplasmic domains. Recently, it was shown that TIP47 regulates the expression of Rab9, as expression of siRNA to TIP47 in transfected cells dramatically decreased the half-life of the Rab9 protein in addition to stabilizing the subcellular localization of Rab9. At least two isoforms of TIP47 are known to exist.Synonyms: 47 kDa mannose 6-phosphate receptor-binding protein, Cargo selection protein TIP47, Mannose-6-phosphate receptor-binding protein 1, Placental protein 17

Gen-ID: 10226

UniProt: O60664