CDC16 Antikörper
Kurzübersicht für CDC16 Antikörper (ABIN498111)
Target
Alle CDC16 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- This antibody detects endogenous levels of Cdc16 protein.
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Kreuzreaktivität (Details)
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Species reactivity (expected):Mouse.
Species reactivity (tested):Human. -
Aufreinigung
- Affinity chromatography using epitope-specific immunogen
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Reinheit
- > 95 % pure by SDS-PAGE
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Applikationshinweise
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Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Phosphate buffered saline (PBS) with 0.05 % Sodium azide, approx. pH 7.2
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- CDC16 (Cell Division Cycle 16 Homolog (S. Cerevisiae) (CDC16))
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Andere Bezeichnung
- CDC16 / APC6
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Hintergrund
- Cell cycle events are regulated by the sequential activation and deactivation of cyclin dependent kinases (Cdks) and by the proteolysis of cyclins. The cell division cycle (Cdc) genes are required at various points in the cell cycle. Cell division cycle protein 16 homolog (CDC16) is a component of the APC (anaphase-promoting complex), which is composed of eight proteins and functions as a protein ubiquitin ligase. The APC complex is a cyclin degradation system that governs exit from mitosis. Each component protein of the APC complex is highly conserved among eukaryotic organisms.Synonyms: ANAPC6, Anaphase-promoting complex subunit 6, CDC16Hs, Cell division cycle protein 16 homolog, Cyclosome subunit 6
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Molekulargewicht
- approx. 72 kDa
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Gen-ID
- 8881
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NCBI Accession
- NP_001072113
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UniProt
- Q13042
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Pathways
- Regulation of Actin Filament Polymerization
Target
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