GABRB3 Antikörper (Internal Region)
Kurzübersicht für GABRB3 Antikörper (Internal Region) (ABIN488000)
Target
Alle GABRB3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Internal Region
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Spezifität
- This antibody reacts to GABRB3.
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Kreuzreaktivität (Details)
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Species reactivity (expected):Mouse, Rat, Canine, Bovine.
Species reactivity (tested):Human. -
Aufreinigung
- Affinity chromatography
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Immunogen
- Peptide with sequence C-EKTAKAKNDRSK, from the internal region of the protein sequence according to NP_000805.1, NP_068712.1.
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Applikationshinweise
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Peptide ELISA: 1/8000. Immunohistochemistry on paraffin sections: Human Cortex shows patchy staining near orat the neuronal cell membrane. Recommended concentration: 2-4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- GABRB3 (gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))
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Andere Bezeichnung
- GABRB3
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Hintergrund
- GABA A Receptor beta 3 is one of at least 13 distinct subunits of a multisubunit chloride channel that serves as the receptor for gamma-aminobutyric acid, the major inhibitory transmitter of the nervous system. The GABAA receptor complex is the molecular target of the benzodiazepine class of tranquilizer drugs, and hence it is also often referred to as the 'benzodiazepine receptor'. The GABAA receptor complex also appears to have distinct binding sites for a variety of other pharmaco-active compounds.Synonyms: GABA A receptor subunit beta-3, GABRB-3, Gamma-aminobutyric acid receptor subunit beta-3
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Gen-ID
- 2562
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NCBI Accession
- NP_000805
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UniProt
- P28472
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Pathways
- Sensory Perception of Sound
Target
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