CCAR1 Antikörper (Internal Region)

Produktnummer ABIN487983

Der Ziege Polyklonal anti-CCAR1 Antikörper (ABIN487983) detektiert spezifisch CCAR1 in WB und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Rind (Kuh) und Schwein.

Kurzübersicht für CCAR1 Antikörper (Internal Region) (ABIN487983)

Target: CCAR1 (Cell Division Cycle and Apoptosis Regulator 1 (CCAR1))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Schwein

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser CCAR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-CCAR1 Antikörper

Bindungsspezifität: Internal Region

Spezifität: This antibody reacts to CCAR1.

Kreuzreaktivität (Details): Species reactivity (expected):Canine, Bovine, Porcine.
Species reactivity (tested):Mouse, Rat.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence RYCKERPSKDKE, from the internal region (near C-Terminus) of the protein sequence according to NP_060707.2.

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/16000. Western blot: Approx 120 kDa band observed in Mouse and Rat Skeletal Muscle lysates(calculated MW of 130 kDa according to Mouse NP_080477.1 and Rat NP_001102005.1). Recommended concentration: 1 - 3 μg/mL. An additional band of unknown identity was also consistently observed at 30 kDa. Thisband was successfully blocked by incubation with the immunizing peptide.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu CCAR1

Target: CCAR1 (Cell Division Cycle and Apoptosis Regulator 1 (CCAR1))

Andere Bezeichnung: CCAR1

Hintergrund: DIS is thought to be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Therefore DIS would have a role in cell cycle progression and/or cell proliferation.Synonyms: CARP1, Cell cycle and apoptosis regulatory protein 1, Cell division cycle and apoptosis regulator protein 1, DIS, Death inducer with SAP domain

Gen-ID: 55749

NCBI Accession: NP_060707

UniProt: Q8IX12