PURA Antikörper (N-Term)

Produktnummer ABIN487030

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PURA in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für PURA Antikörper (N-Term) (ABIN487030)

Target: PURA (Purine-Rich Element Binding Protein A (PURA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PURA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PURA Antikörper

Bindungsspezifität: N-Term

Sequenz: MADRDSGSEQ GGAALGSGGS LGHPGSGSGS GGGGGGGGGG GGSGGGGGGA

Homologie: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PURA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PURA

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 322 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PURA

Target: PURA (Purine-Rich Element Binding Protein A (PURA))

Andere Bezeichnung: PURA

Hintergrund: This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.
Alias Symbols: PUR1, MRD31, PURALPHA, PUR-ALPHA
Protein Interaction Partner: RAF1, UBC, LIN28B, LIN28A, BMI1, TARDBP, IGSF8, ICAM1, IL7R, ZNF638, DDX23, RFC3, RFC2, RB1, PURB, POLA1, CAND1, CUL1, CUL3, EIF2AK2, POU5F1, MEPCE, HNRNPA1, ADAP1, CCNT1, E2F1, SP1, YBX1, CDK5, CNBP, Jvgp5,
Protein Size: 322

Molekulargewicht: 35 kDa

Gen-ID: 5813

NCBI Accession: NM_005859, NP_005850

UniProt: Q00577