IL16 Antikörper
Kurzübersicht für IL16 Antikörper (ABIN453905)
Target
Alle IL16 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- This antibody reacts to Interleukin-16. IL16 antibody clone 323 exhibits no detectable cross-reacting with human albumin serum, Bovine albumin serum and other human cytokines or growth factors tested such as IL-1beta, IL-8, IL-7 MCAF, TGF-beta 1, EGF, bFGF, GM-CSF, M-CSF, TNF-alpha.
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human.
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Aufreinigung
- Affinity Chromatography on Protein G.
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Immunogen
- Purified recombinant Human IL-16.
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Isotyp
- IgG2b
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Applikationshinweise
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ELISA. Western Blot: IL16 antibody at a concentration of 2.5 μg/mL will allow visualization of 1 μg/lane of human IL-16.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Rekonstitution
- Restore with double distillated water to adjust the final concentration to 1.00 mg/mL.
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Buffer
- 0.01 M PBS, pH 7.2 without preservatives.
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Konservierungsmittel
- Without preservative
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Handhabung
- This product is photosensitive and should be protected from light
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store the antibody at 2 - 8 °C. DO NOT FREEZE!
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- IL16 (Interleukin 16 (IL16))
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Andere Bezeichnung
- Interleukin-16 / IL16
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Hintergrund
- Interleukin-16 (IL16) is a proinflammatory cytokine that is chemotactic for CD4+ T lymphocytes, monocytes, and eosinophils. IL16 is synthesized as a precursor molecule (pro IL16) of approximately 68 kDa and 631 amino acid residues lacking a signal peptide. The sequence and structure of IL16 is conserved across species. In addition to inducing chemotaxis, IL16 upregulates the IL2 receptor and upregulates HLADR expression. It also inhibits T cell receptor (TCR)/CD3 dependent activation, and suppresses HIV1 replication in vitro. Sources of IL16 include epithelial cells, mast cells, T lymphocytes (CD4+ and CD8+), macrophages, synovial fibroblasts, and eosinophils.Synonyms: IL-16, LCF, Lymphocyte chemoattractant factor
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Gen-ID
- 3603
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NCBI Accession
- NP_004504
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UniProt
- Q14005
Target
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