M. tuberculosis Antikörper
Kurzübersicht für M. tuberculosis Antikörper (ABIN452549)
Target
Alle M. tuberculosis Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Produktmerkmale
- Synonyms: M. tuberculosis, TB
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Aufreinigung
- Affinity Chromatography on Protein G.
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Immunogen
- A recombinant M. tuberculosis protein cloned from virulent strain H37Rv with primerstargeting the 38Kd antigen.
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Isotyp
- IgG2a
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Applikationshinweise
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ELISA: Reactive to the immunogen in ELISA assay. Western Blotting: A band corresponding to the immunogen is detected.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Rekonstitution
- Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.
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Buffer
- 0.01 M PBS, pH 7.0 without preservatives.
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Konservierungsmittel
- Without preservative
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Lagerung
- -20 °C
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Informationen zur Lagerung
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Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Haltbarkeit
- 12 months
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- M. tuberculosis (Mycobacterium Tuberculosis)
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Substanzklasse
- Bacteria
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Hintergrund
- Mycobacterium tuberculosis is the most common cause of tuberculosis. Primary infection begins with inhalation of 1 to 10 aerosolised bacilli. The pathogenicity of the organism is determined by its ability to escape host immune responses as well as eliciting delayed hypersensitivity. Alveolar macrophages engulf the invading cells but are unable to mount an effective defense. Several virulence factors are responsible for this apparent failure, most notably in the mycobacterial cell wall are the cord factor, lipoarabinomannan, and the 65 kd heat shock protein or HSP65. The emergence of new strains of resistant Mycobacterium tuberculosis has created new interest in clinical diagnosis. Studies have shown immunohistochemical techniques to be superior to conventional special stains. Thus the demonstration of mycobacterial antigens are not only useful in establishing mycobacterial aetiology, but can also be used as an alternative method to the conventional Ziehl-Neelsen method.Synonyms: M. tuberculosis, TB
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Molekulargewicht
- 38 kDa Ag
Target
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