ACADS Antikörper (Middle Region)

Produktnummer ABIN406378

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ACADS in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio), Rind (Kuh) und Hund.Es wurde in 1 Publikation zitiert.

Kurzübersicht für ACADS Antikörper (Middle Region) (ABIN406378)

Target: ACADS (Acads) (Acyl-CoA Dehydrogenase, C-2 To C-3 Short Chain (Acads))

Reaktivität: Human, Maus, Ratte, Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio), Rind (Kuh), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACADS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ACADS Antikörper

Bindungsspezifität: Middle Region

Sequenz: FTSGDKIGCF ALSEPGNGSD AGAASTTARA EGDSWVLNGT KAWITNAWEA

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ACADS. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ACADS

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 412 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ACADS Antikörper (ABIN406378)

Tein, Elpeleg, Ben-Zeev, Korman, Lossos, Lev, Lerman-Sagie, Leshinsky-Silver, Vockley, Berry, Lamhonwah, Matern, Roe, Gregersen: "Short-chain acyl-CoA dehydrogenase gene mutation (c.319C>T) presents with clinical heterogeneity and is candidate founder mutation in individuals of Ashkenazi Jewish origin." in: Molecular genetics and metabolism, Vol. 93, Issue 2, pp. 179-89, (2008) (PubMed).

Details zu ACADS

Target: ACADS (Acads) (Acyl-CoA Dehydrogenase, C-2 To C-3 Short Chain (Acads))

Andere Bezeichnung: ACADS

Hintergrund: ACADS is a a tetrameric mitochondrial flavoprotein, which is a member of the acyl-CoA dehydrogenase family. This enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Mutations in this gene have been associated with Short Chain Acyl-CoA Dehydrogenase Deficiency. This gene encodes a a tetrameric mitochondrial flavoprotein, which is a member of the acyl-CoA dehydrogenase family. This enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Mutations in this gene have been associated with Short Chain Acyl-CoA Dehydrogenase Deficiency. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ACAD3, SCAD
Protein Interaction Partner: IRF7,
Protein Size: 412

Molekulargewicht: 42 kDa

Gen-ID: 35

NCBI Accession: NM_000017, NP_000008

UniProt: P16219

Pathways: Monocarboxylic Acid Catabolic Process