SLC5A5 Antikörper (Middle Region)

Produktnummer ABIN405589

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SLC5A5 in WB. Es zeigt Reaktivität gegenüber Proben von Human.Es wurde in 1 Publikation zitiert.

Kurzübersicht für SLC5A5 Antikörper (Middle Region) (ABIN405589)

Target: SLC5A5 (Solute Carrier Family 5 (Sodium/iodide Cotransporter), Member 5 (SLC5A5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC5A5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SLC5A5 Antikörper

Bindungsspezifität: Middle Region

Sequenz: PSEQTMRVLP SSAARCVALS VNASGLLDPA LLPANDSSRA PSSGMDASRP

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SLC5A5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SLC5A5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 643 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SLC5A5 Antikörper (ABIN405589)

Liu, Lunsford, Tong, Ashitate, Gibbs, Yu, Choi, Henske, Frangioni: "Real-time monitoring of tumorigenesis, dissemination, & drug response in a preclinical model of lymphangioleiomyomatosis/tuberous sclerosis complex." in: PLoS ONE, Vol. 7, Issue 6, pp. e38589, (2012) (PubMed).

Details zu SLC5A5

Target: SLC5A5 (Solute Carrier Family 5 (Sodium/iodide Cotransporter), Member 5 (SLC5A5))

Andere Bezeichnung: SLC5A5

Hintergrund: The sodium-iodide symporter (NIS, or SLC5A5) is a key plasma membrane protein that mediates active I- uptake in thyroid, lactating breast, and other tissues with an electrogenic stoichiometry of 2 Na+ per I-. In thyroid, NIS-mediated I- uptake is the first step in the biosynthesis of iodine-containing thyroid hormones.The sodium-iodide symporter (NIS, or SLC5A5) is a key plasma membrane protein that mediates active I- uptake in thyroid, lactating breast, and other tissues with an electrogenic stoichiometry of 2 Na+ per I-. In thyroid, NIS-mediated I- uptake is the first step in the biosynthesis of iodine-containing thyroid hormones (Dohan et al., 2007 [PubMed 18077370]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: NIS, TDH1
Protein Interaction Partner: ERBB2IP, SLC5A5,
Protein Size: 643

Molekulargewicht: 69 kDa

Gen-ID: 6528

NCBI Accession: NM_000453, NP_000444

UniProt: Q92911