CNBP Antikörper (N-Term)
Kurzübersicht für CNBP Antikörper (N-Term) (ABIN404967)
Target
Alle CNBP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- SSNECFKCGR SGHWARECPT GGGRGRGMRS RGRGGFTSDR GFQFVSSSLP
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Homologie
- Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against CNBP. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human CNBP
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 177 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CNBP (CCHC-Type Zinc Finger, Nucleic Acid Binding Protein (CNBP))
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Andere Bezeichnung
- CNBP
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Hintergrund
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CNBP is a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene.This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CNBP1, DM2, PROMM, RNF163, ZCCHC22, ZNF9
Protein Interaction Partner: UBC, EZH2, BMI1, SUZ12, RNF2, BZW2, FERMT2, PFAS, EIF6, HSPA9, DFFA, MAPK14, PAN2, VCAM1, ITGA4, KCND3, Mis12, Cnbp, ZWINT, MYH4, FKTN, PCBP2, RPL31, HNRNPA3, BRIX1, APOBEC3C, RBMX, RSL1D1, RPL36, HNRNPUL1, EBNA1BP2, IGF2BP3, IGF2BP1, SYNCRIP, HNRNPR, DAP
Protein Size: 177 -
Molekulargewicht
- 19 kDa
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Gen-ID
- 7555
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NCBI Accession
- NM_003418, NP_003409
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UniProt
- P62633
Target
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