TAF2 Antikörper (Middle Region)

Produktnummer ABIN404873

Der Kaninchen Polyklonal anti-TAF2 Antikörper wird verwendet zum Nachweis von TAF2 in Proben von Human, Maus, Pferd, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen und Zebrafisch (Danio rerio). Er wurde validiert für WB und ChIP.

Kurzübersicht für TAF2 Antikörper (Middle Region) (ABIN404873)

Target: TAF2 (TAF2 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 150kDa (TAF2))

Reaktivität: Human, Maus, Pferd, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TAF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Produktdetails anti-TAF2 Antikörper

Bindungsspezifität: Middle Region

Sequenz: RKRNVLELEI KQDYTSPGTQ KYVGPLKVTV QELDGSFNHT LQIEENSLKH

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against TAF2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TAF2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1199 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TAF2

Target: TAF2 (TAF2 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 150kDa (TAF2))

Andere Bezeichnung: TAF2

Hintergrund: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF2 is one of the larger subunits of TFIID that is stably associated with the TFIID complex. It contributes to interactions at and downstream of the transcription initiation site, interactions that help determine transcription complex response to activators.Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the larger subunits of TFIID that is stably associated with the TFIID complex. It contributes to interactions at and downstream of the transcription initiation site, interactions that help determine transcription complex response to activators. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CIF150, TAF2B, TAFII150
Protein Interaction Partner: SHFM1, SOX2, SIRT1, RNPS1, MED26, HIST3H3, TAF9, TAF6, TAF1, ISG15, ESR1, TAF10, ELAVL1, UBC, TAF8, TERF2, TERF1, TBP, KDM5B, TAF13, TAF12, TAF11, TAF5, TAF4, TAF7,
Protein Size: 1199

Molekulargewicht: 137 kDa

Gen-ID: 6873

NCBI Accession: NM_003184, NP_003175

UniProt: Q6P1X5