TAF5L Antikörper (Middle Region)

Produktnummer ABIN404809

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TAF5L in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Hund, Kaninchen, Ratte, Meerschweinchen, Pferd, Rind (Kuh) und Zebrafisch (Danio rerio).

Kurzübersicht für TAF5L Antikörper (Middle Region) (ABIN404809)

Target: TAF5L (TAF5-Like RNA Polymerase II, P300/CBP-Associated Factor (PCAF)-Associated Factor, 65kDa (TAF5L))

Reaktivität: Human, Maus, Hund, Kaninchen, Ratte, Meerschweinchen, Pferd, Rind (Kuh), Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TAF5L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TAF5L Antikörper

Bindungsspezifität: Middle Region

Sequenz: CVKFHPNSNY LATGSTDKTV RLWSAQQGNS VRLFTGHRGP VLSLAFSPNG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TAF5L. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TAF5L

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 589 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TAF5L

Target: TAF5L (TAF5-Like RNA Polymerase II, P300/CBP-Associated Factor (PCAF)-Associated Factor, 65kDa (TAF5L))

Andere Bezeichnung: TAF5L

Hintergrund: TAF5L functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex.The product of this gene belongs to the WD-repeat TAF5 family of proteins. This gene encodes a protein that is a component of the PCAF histone acetylase complex. The PCAF histone acetylase complex, which is composed of more than 20 polypeptides some of which are TAFs, is required for myogenic transcription and differentiation. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. The encoded protein is structurally similar to one of the histone-like TAFs, TAF5. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Alias Symbols: PAF65B
Protein Interaction Partner: HECW2, UBC, KAT2B, LSM11, TADA3, TAF10, ELAVL1, TSC22D1, TTR, H2AFX, CDKN1A, ANXA7, KAT2A, TP53, ATXN7, CEBPE, USP22, ATXN7L3, SUPT3H, TAF9, MYC,
Protein Size: 589

Molekulargewicht: 66 kDa

Gen-ID: 27097

NCBI Accession: NM_014409, NP_055224

UniProt: O75529