Selenoprotein W Antikörper

Produktnummer ABIN401399

Der Kaninchen Polyklonal anti-Selenoprotein W Antikörper wird verwendet zum Nachweis von Selenoprotein W in Proben von Ratte und Maus. Er wurde validiert für WB und EIA.

Kurzübersicht für Selenoprotein W Antikörper (ABIN401399)

Target: Selenoprotein W (SEPW1) (Selenoprotein W, 1 (SEPW1))

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Selenoprotein W Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-Selenoprotein W Antikörper

Spezifität: This antibody is specific for Selenoprotein W.

Kreuzreaktivität (Details): Species reactivity (expected):Rat.
Species reactivity (tested):Mouse.

Aufreinigung: Affinity chromatography

Immunogen: Recombinant protein corresponding to full-length mouse SelW protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1/100,000. Western Blot: 1/1,000 - 1/5,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.96 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Details zu Selenoprotein W

Target: Selenoprotein W (SEPW1) (Selenoprotein W, 1 (SEPW1))

Andere Bezeichnung: Selenoprotein W (SELW)

Hintergrund: Selenoprotein W was first purified and characterized from rat skeletal muscle. The function of selenoprotein W is not entirely clear, but the presence of the bound glutathione moiety indicates that SelW is thought to function in oxidation-reduction catalysis and may play a role in selenium deficiency disorders such as white muscle disease in sheep and Keshan disease in humans. Recently, overexpression of SelW was shown to be glutathione dependent and was shown to markedly reduce the sensitivity of cell lines to H2O2 cytotoxicity.Synonyms: SEPW, SEPW1

Gen-ID: 20364

NCBI Accession: NP_033182

UniProt: P63300

Pathways: Cell RedoxHomeostasis