DAXX Antikörper (AA 261-274)

Produktnummer ABIN401370

Der Kaninchen Polyklonal anti-DAXX Antikörper (ABIN401370) detektiert spezifisch DAXX in WB und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für DAXX Antikörper (AA 261-274) (ABIN401370)

Target: DAXX (Death-Domain Associated Protein (DAXX))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DAXX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-DAXX Antikörper

Bindungsspezifität: AA 261-274

Spezifität: This antibody is directed against DAXX protein.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity Purified

Immunogen: Synthetic peptide corresponding to amino acids 261-274 of human DAXX protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1/7,000 - 1/45,000. Western Blot: 1/200 - 1/2000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.06 mg/mL (by UV absorbance at 280)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Details zu DAXX

Target: DAXX (Death-Domain Associated Protein (DAXX))

Andere Bezeichnung: DAXX

Hintergrund: DAXX, the Death domain-associated protein 6 (also named Fas death domain-associated protein, ETS1-associated protein 1 or EAP1), functions in part as a transcriptional co-repressor through its interaction with a number of nuclear, DNA-associated proteins, such as histone deacetylase II, core histones H2A, H2B, H3 and H4, and Dek, a chromatinassociated protein reported to change the topology of DNA in chromatin in vitro (1). DAXX also interacts with p73, and is involved in the regulation of the cell cycle and apoptosis through transcriptional regulation of p53 and possibly its family members (2).Synonyms: BING2, DAP6, Death domain-associated protein 6, EAP1, ETS1-associated protein 1, Fas death domain-associated protein

Gen-ID: 1616

NCBI Accession: NP_001135441

UniProt: Q9UER7

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway