CDC16 Antikörper (pThr580)

Produktnummer ABIN401306

Der Kaninchen Polyklonal anti-CDC16 Antikörper wird verwendet zum Nachweis von CDC16 in Proben von Human. Er wurde validiert für WB und EIA.

Kurzübersicht für CDC16 Antikörper (pThr580) (ABIN401306)

Target: CDC16 (Cell Division Cycle 16 Homolog (S. Cerevisiae) (CDC16))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDC16 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-CDC16 Antikörper

Bindungsspezifität: AA 575-588, pThr580

Spezifität: This antibody is specific for phosphorylated APC6 protein at the pT580 residue.

Aufreinigung: Affinity chromatography

Immunogen: Synthetic peptide corresponding to amino acids 575-588 of Human Apc6 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000 - 1/10,000. Western Blot: 1/500 - 1/3,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.97 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Details zu CDC16

Target: CDC16 (Cell Division Cycle 16 Homolog (S. Cerevisiae) (CDC16))

Andere Bezeichnung: CDC16 / APC6

Hintergrund: APC6 (also known as Cell division cycle protein 16 homolog (CDC16Hs), anaphase promoting complex subunit 6, and cyclosome subunit 6) is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C is composed of at least 11 subunits. APC6 interacts with PPP5C and CDC20. This protein colocalizes with CDC27 to the centrosome at all stages of the cell cycle and to the mitotic spindle. Splice variants have been described for this protein.Synonyms: ANAPC6, Anaphase-promoting complex subunit 6, CDC16Hs, Cell division cycle protein 16 homolog, Cyclosome subunit 6

Gen-ID: 8881

NCBI Accession: NP_001072113

UniProt: Q13042

Pathways: Regulation of Actin Filament Polymerization