APC1 Antikörper (pSer355)

Produktnummer ABIN401294

Der Kaninchen Polyklonal anti-APC1 Antikörper wird verwendet zum Nachweis von APC1 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Huhn und Schimpanse. Er wurde validiert für WB und EIA.

Kurzübersicht für APC1 Antikörper (pSer355) (ABIN401294)

Target: APC1 (ANAPC1) (Anaphase Promoting Complex Subunit 1 (ANAPC1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Huhn, Schimpanse

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-APC1 Antikörper

Bindungsspezifität: AA 351-359, pSer355

Spezifität: This antibody is specific for phosphorylated APC1 protein at the pS355 residue.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Canine, Bovine, Chimpanzee, Chicken.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Immunogen: Synthetic peptide corresponding to amino acids 351-359 of Human Apc1 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10,000 - 1/40,000. Western Blot: 1/200 - 1/2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.55 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Details zu APC1

Target: APC1 (ANAPC1) (Anaphase Promoting Complex Subunit 1 (ANAPC1))

Andere Bezeichnung: APC1 / ANAPC1

Hintergrund: APC1 (also known as Anaphase promoting complex subunit 1, Cyclosome subunit 1, Protein Tsg24, Mitotic checkpoint regulator and ANAPC1) is 1 of at least 11 subunits of the anaphase-promoting complex (APC), which functions at the metaphase-to-anaphase transition of the cell cycle and is regulated by spindle checkpoint proteins. The APC is an E3 ubiquitin ligase that targets cell cycle regulatory proteins for degradation by the proteasome, thereby allowing progression through the cell cycle.Synonyms: Anaphase-promoting complex subunit 1, Cyclosome subunit 1, MCPR, Mitotic checkpoint regulator, TSG24, Testis-specific gene 24 protein

Gen-ID: 64682

NCBI Accession: NP_073153

UniProt: Q9H1A4