gamma 1 Adaptin Antikörper (AA 646-659)

Produktnummer ABIN401169

Der Ziege Polyklonal anti-gamma 1 Adaptin Antikörper (ABIN401169) detektiert spezifisch gamma 1 Adaptin in WB und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Schimpanse und Orang-Utan.

Kurzübersicht für gamma 1 Adaptin Antikörper (AA 646-659) (ABIN401169)

Target: gamma 1 Adaptin (AP1G1) (Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1))

Reaktivität: Human, Schimpanse, Orang-Utan

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser gamma 1 Adaptin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-gamma 1 Adaptin Antikörper

Bindungsspezifität: AA 646-659

Spezifität: This antibody is directed against AP1G1.

Kreuzreaktivität (Details): Species reactivity (expected):Chimpanzee, Orangutan, Mouse, Rat, Canine, Chicken.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Immunogen: Synthetic peptide corresponding aa 646-659 of Human AP1G1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1/2,000 - 1/8,000. Western Blot: 1/500 - 1/2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.7 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Details zu gamma 1 Adaptin

Target: gamma 1 Adaptin (AP1G1) (Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1))

Andere Bezeichnung: AP1 Complex Subunit gamma-1

Hintergrund: AP1G1 (also known as gamma 1 subunit of adaptor -related protein complex 1, Gammaadaptin, Adaptor protein complex AP-1 gamma-1 subunit, Golgi adaptor HA1/AP1 adaptin gamma-1 subunit and Clathrin assembly protein complex 1 gamma-1 large chain) is a subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late- Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. AP1G1 is localized to the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex and is widely expressed.Synonyms: ADTG, AP1G1, Adapter-related protein complex 1 subunit gamma-1, Adaptor protein complex AP-1 subunit gamma-1, CLAPG1, Clathrin assembly protein complex 1 gamma-1 large chain, Golgi adaptor HA1/AP1, gamma 1 Adaptin, gamma Adaptin

Gen-ID: 164

NCBI Accession: NP_001025178

UniProt: O43747