COL18A1 Antikörper (Chain alpha 1)

Produktnummer ABIN400737

Der Maus Monoklonal anti-COL18A1 Antikörper (Klon 1873-46) (ABIN400737) detektiert spezifisch COL18A1 in WB und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für COL18A1 Antikörper (Chain alpha 1) (ABIN400737)

Target: COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser COL18A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 1873-46

Produktdetails anti-COL18A1 Antikörper

Bindungsspezifität: Chain alpha 1

Spezifität: Recognizes Mouse Endostatin (Mr 22 kDa), an unidentified protein is also weakly detected (Mr 52 kDa).

Kreuzreaktivität (Details): Species reactivity (expected):Human and Rat.
Species reactivity (tested):Mouse.

Produktmerkmale: Synonyms: COL18A1, Endostatin, KNO1

Aufreinigung: Thiophilic Adsorption Chromatography.

Immunogen: Full-length Recombinant Murine Endostatin.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot (Immunoblot). Immunohistochemistry on Paraffin Sections: 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 50 mM Sodium Phosphate, pH 8.0 containing 0.05 % Sodium Azide, before the addition of Glycerol to 30 %.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu COL18A1

Target: COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))

Hintergrund: Endostatin (20-22 kDa), a cleaved product of the C-terminal domain of collagen XVIII, is an endogenous angiogenesis inhibitor. It was originally found in conditioned media from a murine endothelial tumor cell line, hemangioendothelioma. Endostatin inhibits endothelial cell migration (in vivo and in vitro) and induces endothelial cell apoptosis. It inhibits tumor growth and impairs blood vessel maturation in wound healing. Endostatin has an important role in endothelial cell adhesion and cytoskeletal organization. Endostatin can be found in vessel walls (elastic fibers) and basement membranes.Synonyms: COL18A1, Endostatin, KNO1

Gen-ID: 80781

UniProt: P39060