NUAK2 Antikörper (N-Term)

Produktnummer ABIN391234

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch NUAK2 in WB. Es zeigt Reaktivität gegenüber Proben von Human.Es wurde in 1 Publikation zitiert.

Kurzübersicht für NUAK2 Antikörper (N-Term) (ABIN391234)

Target: NUAK2 (NUAK Family, SNF1-Like Kinase, 2 (NUAK2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUAK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB8576

Produktdetails anti-NUAK2 Antikörper

Bindungsspezifität: AA 67-96, N-Term

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This NUAK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 amino acids from the N-terminal region of human NUAK2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-NUAK2 Antikörper (ABIN391234)

Yamamoto, Takashima, Shintani, Yamazaki, Seguchi, Nakano, Higo, Kato, Liao, Asano, Minamino, Matsumura, Takeda, Kitakaze: "Identification of a novel substrate for TNFalpha-induced kinase NUAK2." in: Biochemical and biophysical research communications, Vol. 365, Issue 3, pp. 541-7, (2008) (PubMed).

Details zu NUAK2

Target: NUAK2 (NUAK Family, SNF1-Like Kinase, 2 (NUAK2))

Andere Bezeichnung: NUAK2

Hintergrund: Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells.

Molekulargewicht: 69612

Gen-ID: 81788

NCBI Accession: NP_112214

UniProt: Q9H093