PARP6 Antikörper (C-Term)

Produktnummer ABIN390249

Der Kaninchen Polyklonal anti-PARP6 Antikörper (Klon RB14167) (ABIN390249) detektiert spezifisch PARP6 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für PARP6 Antikörper (C-Term) (ABIN390249)

Target: PARP6 (Poly (ADP-Ribose) Polymerase Family, Member 6 (PARP6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PARP6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB14167

Produktdetails anti-PARP6 Antikörper

Bindungsspezifität: AA 553-583, C-Term

Homologie: M

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This Parp6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 553-583 amino acids from the C-terminal region of human Parp6.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu PARP6

Target: PARP6 (Poly (ADP-Ribose) Polymerase Family, Member 6 (PARP6))

Andere Bezeichnung: Parp6

Hintergrund: Poly(ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. Poly(ADP-ribose) polymerases (PARPs) now constitute a large family of 18 proteins, encoded by different genes and displaying a conserved catalytic domain in which PARP-1 (113 kDa), the founding member, and PARP-2 (62 kDa) are so far the sole enzymes whose catalytic activity has been shown to be immediately stimulated by DNA strand breaks. A large repertoire of sequences encoding novel PARPs now extends considerably the field of poly(ADP-ribosyl)ation reactions to various aspects of the cell biology including cell proliferation and cell death. Some of these new members interact with each other, share common partners and common subcellular localizations suggesting possible fine tuning in the regulation of this post-translational modification of proteins.

Molekulargewicht: 71115

Gen-ID: 56965

NCBI Accession: NP_064599

UniProt: Q2NL67