GGA1 Antikörper (N-Term)

Produktnummer ABIN389018

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-GGA1 Antikörper wird verwendet zum Nachweis von GGA1 in Proben von Human und Maus. Er wurde validiert für WB und IF.

Kurzübersicht für GGA1 Antikörper (N-Term) (ABIN389018)

Target: GGA1 (Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 1 (GGA1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GGA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Klon: RB4932

Produktdetails anti-GGA1 Antikörper

Bindungsspezifität: AA 1-30, N-Term

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This GGA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GGA1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-GGA1 Antikörper (ABIN389018)

von Arnim, Spoelgen, Peltan, Deng, Courchesne, Koker, Matsui, Kowa, Lichtenthaler, Irizarry, Hyman: "GGA1 acts as a spatial switch altering amyloid precursor protein trafficking and processing." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 26, Issue 39, pp. 9913-22, (2006) (PubMed).

Details zu GGA1

Target: GGA1 (Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 1 (GGA1))

Andere Bezeichnung: GGA1

Hintergrund: GGA1 is a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins.

Molekulargewicht: 70384

Gen-ID: 26088

NCBI Accession: NP_001001560, NP_001001561, NP_001166158, NP_001166159, NP_037497

UniProt: Q9UJY5