Growth Differentiation Factor 2 (GDF2) (N-Term) Antikörper

Antigen: Growth Differentiation Factor 2 (GDF2)

Synonyme: BMP9, BMP-9, Bmp9, MGC124253, MGC124255, MGC124256, bmp9

Epitope: N-Term

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Western Blot (WB), Immunhistochemie (IHC), ELISA

Zertifikate: ISO 9001:2008

Produktnummer: ABIN388817

Produktbeschreibung

Produktmerkmale: Purified Rabbit Polyclonal Antibody (Pab)

Weitere Bezeichnung: BMP9 (GDF2) (N-term)

Gen-ID: 2658

Swiss-Prot: Q9UK05

Immunogen: This BMP9 (GDF2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human GDF2.

Isotyp: Ig  (Passende Sekundärantikörper)

Spezifität: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human GDF2.

Molekulargewicht: 47320 DA

Anwendungen

Applikationshinweise: The suggested dilution is: ELISA~~1:1,000 Western blotting~~1:100~500 Immunohistochemistry~~1:50~100

Konzentration: 0.25 mg/ml

Reinigung: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Lagerung: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Forschungsgebiet: Neurologie

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

The anti-hGDF2 N-term Pab (ABIN388817) is used in Western blot to detect hGDF2 in mouse liver tissue lysate.

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. clinical relevance has not been evaluated. BC = breast carcinoma. HC = hepatocarcinoma.

Western blot analysis of GDF2 (arrow) using rabbit polyclonal GDF2-K23 (ABIN388817). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the GDF2 gene.

Publikationen

Publikationen: Herrera, van Dinther, Ten Dijke et al.: "Autocrine bone morphogenetic protein-9 signals through activin receptor-like kinase-2/Smad1/Smad4 to promote ovarian cancer cell proliferation." in: Cancer research, Vol. 69, Issue 24, pp. 9254-62, 2009 (PubMed).