APOBEC1 Antikörper (N-Term)

Produktnummer ABIN388144

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch APOBEC1 in WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für APOBEC1 Antikörper (N-Term) (ABIN388144)

Target: APOBEC1 (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide 1 (APOBEC1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APOBEC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB1746

Produktdetails anti-APOBEC1 Antikörper

Bindungsspezifität: AA 7-36, N-Term

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This Apobec1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-36 amino acids from the N-terminal region of human Apobec1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu APOBEC1

Target: APOBEC1 (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide 1 (APOBEC1))

Andere Bezeichnung: Apobec1

Hintergrund: APOBEC1 is involved in the production of apolipoprotein B (apoB)-48 from apoB-100. The gene spans 18 kb and contains five exons, all of which are translated. Alternative splicing produces a variant transcript that lacks exon 2 and encodes a novel 36-amino acid peptide. The exon 2-skipped transcript accounts for approximately 50 % of APOBEC1 mRNA in the adult small intestine and up to 90 % of APOBEC1 mRNA in the developing gut. Exon 2-skipping may thus be a quantitatively important mechanism for regulating the expression of this gene in the gastrointestinal tract.

Molekulargewicht: 28192

Gen-ID: 339

NCBI Accession: NP_001635

UniProt: P41238