SLC29A1 Antikörper (AA 234-263)

Produktnummer ABIN387941

Es sind 2+ Publikationen für dieses Produkt verfügbar. Der Kaninchen Polyklonal anti-SLC29A1 Antikörper wird verwendet zum Nachweis von SLC29A1 in Proben von Human und Maus. Er wurde validiert für WB.

Kurzübersicht für SLC29A1 Antikörper (AA 234-263) (ABIN387941)

Target: SLC29A1 (Solute Carrier Family 29 (Nucleoside Transporters), Member 1 (SLC29A1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC29A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB28016

Produktdetails anti-SLC29A1 Antikörper

Bindungsspezifität: AA 234-263

Homologie: Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ENT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-263 amino acids from the Central region of rat ENT1(O54698).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:2000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Haltbarkeit: 6 months

Referenzen für anti-SLC29A1 Antikörper (ABIN387941)

Niemann, Haufs-Brusberg, Puetz, Feickert, Jaeckstein, Hoffmann, Zurkovic, Heine, Trautmann, Müller, Tönjes, Schlein, Jafari, Eltzschig, Gnad, Blüher, Krahmer, Kovacs, Heeren, Pfeifer: "Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine." in: Nature, (2022) (PubMed).

Ibarra, Pfeiffer: "Reduced ribavirin antiviral efficacy via nucleoside transporter-mediated drug resistance." in: Journal of virology, Vol. 83, Issue 9, pp. 4538-47, (2009) (PubMed).

Details zu SLC29A1

Target: SLC29A1 (Solute Carrier Family 29 (Nucleoside Transporters), Member 1 (SLC29A1))

Andere Bezeichnung: ENT1

Hintergrund: ENT1 is a member of the equilibrative nucleoside transporter family. It is a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies.

Molekulargewicht: 50219

Gen-ID: 2030

NCBI Accession: NP_001071642, NP_001071643, NP_001071644, NP_001071645, NP_004946

UniProt: Q99808

Pathways: Carbohydrate Homeostasis, Synaptic Membrane