H2-D1 Antikörper

Produktnummer ABIN375490

Dieser Maus Monoklonal Antikörper detektiert spezifisch H2-D1 in FACS, IP, CMCD, BR und IHC (fro). Es zeigt Reaktivität gegenüber Proben von Maus.

Kurzübersicht für H2-D1 Antikörper (ABIN375490)

Target: H2-D1 (Histocompatibility 2, D Region Locus 1 (H2-D1))

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser H2-D1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Complement Mediated Cell Depletion (CMCD), Blocking Reagent (BR), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: 28-14-8

Produktdetails anti-H2-D1 Antikörper

Verwendungszweck: Mouse Anti-Mouse H-2Db-LE/AF

Spezifität: Mouse H-2Db

Produktmerkmale: Low Endotoxin/Azide Free Anti-Mouse H-2Db antibody for use in flow cytometry, immunohistochemistry, immunoprecipitation, CMCD, and blocking assays.

Endotoxin-Niveau: Low Endotoxin

Immunogen: C3H.SW mouse splenocytes

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Konservierungsmittel: Azide free

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C

Details zu H2-D1

Target: H2-D1 (Histocompatibility 2, D Region Locus 1 (H2-D1))

Andere Bezeichnung: H-2Db

Hintergrund: The 'classical' MHC Class I molecules are histocompatibility antigens encoded by the H-2 gene complex and consist of heterodimers of highly polymorphic α chains noncovalently associated with the invariant β 2-microglobulin. These antigens are expressed on most nucleated cells but expression varies on different cell types. MHC Class I molecules present endogenously synthesized peptides to CD8 + T lymphocytes, which are usually cytotoxic T cells. MHC Class I antigens expressed on thymic epithelial cells regulate the positive and negative selection of CD8 + T cells during T cell ontogeny.

Gen-ID: 14964

UniProt: P01899

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process