P2RX4 Antikörper (C-Term)

Produktnummer ABIN375223

Dieser Ziege Polyklonal Antikörper detektiert spezifisch P2RX4 in WB und EIA. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Maus, Rind (Kuh) und Hund. Es wurde in 13+ Publikationen zitiert.

Kurzübersicht für P2RX4 Antikörper (C-Term) (ABIN375223)

Target: P2RX4 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 4 (P2RX4))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser P2RX4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-P2RX4 Antikörper

Bindungsspezifität: C-Term

Sequenz: C-YREKKYKYVE DYEQ

Spezifität: This antibody detects P2X4.

Kreuzreaktivität (Details): Species reactivity (expected):Rat, Canine (Dog), Bovine.
Species reactivity (tested):Human, Mouse.

Aufreinigung: Affinity Chromatography

Immunogen: Peptide with sequence from the C-Terminus of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/32000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-P2RX4 Antikörper (ABIN375223)

Girón, Vílchez, Shreeram, Salto, Manzano, Cabrera, Campos, Edens, Rueda, López-Pedrosa: "β-Hydroxy-β-methylbutyrate (HMB) normalizes dexamethasone-induced autophagy-lysosomal pathway in skeletal muscle." in: PLoS ONE, Vol. 10, Issue 2, pp. e0117520, (2016) (PubMed).

Millet, Martin, Bonnefoy, Saas, Mocek, Alkan, Terrier, Kerstein, Tamassia, Satyanarayanan, Ariel, Ribeil, Guillevin, Cassatella, Mueller, Thieblemont, Lamprecht, Mouthon, Perruche, Witko-Sarsat: "Proteinase 3 on apoptotic cells disrupts immune silencing in autoimmune vasculitis." in: The Journal of clinical investigation, Vol. 125, Issue 11, pp. 4107-21, (2016) (PubMed).

Moshfegh, Aires, Kisielow, Vogel: "A gonogenic stimulated transition of mouse embryonic stem cells with enhanced control of diverse differentiation pathways." in: Scientific reports, Vol. 6, pp. 25104, (2016) (PubMed).

Nassar, Halle, Plagemann, Tzschentke et al.: "Detection of long-term influence of prenatal temperature stimulation on hypothalamic type-II iodothyronine deiodinase in juvenile female broiler chickens using a novel immunohistochemical ..." in: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, Vol. 179, pp. 120-4, (2015) (PubMed).

Ott, Plitzko, Krischkowski, Reichmann, Bittner, Mendel, Kunze, Clement, Havemeyer: "Reduction of sulfamethoxazole hydroxylamine (SMX-HA) by the mitochondrial amidoxime reducing component (mARC)." in: Chemical research in toxicology, Vol. 27, Issue 10, pp. 1687-95, (2015) (PubMed).

Grill, Neumann, Hiltwein, Kolligs, Schneider: "Intestinal E-cadherin Deficiency Aggravates Dextran Sodium Sulfate-Induced Colitis." in: Digestive diseases and sciences, Vol. 60, Issue 4, pp. 895-902, (2015) (PubMed).

Raz, Buijze, Raz, Verwey, Anvar, Aartsma-Rus, van der Maarel: "A novel feed-forward loop between ARIH2 E3-ligase and PABPN1 regulates aging-associated muscle degeneration." in: The American journal of pathology, Vol. 184, Issue 4, pp. 1119-31, (2014) (PubMed).

Cruz-Orengo, Daniels, Dorsey, Basak, Grajales-Reyes, McCandless, Piccio, Schmidt, Cross, Crosby, Klein: "Enhanced sphingosine-1-phosphate receptor 2 expression underlies female CNS autoimmunity susceptibility." in: The Journal of clinical investigation, Vol. 124, Issue 6, pp. 2571-84, (2014) (PubMed).

Morgan, Cheepala, Wang, Neale, Adachi, Nachagari, Leggas, Zhao, Boyd, Venkataramanan, Schuetz: "Deregulated hepatic metabolism exacerbates impaired testosterone production in Mrp4-deficient mice." in: The Journal of biological chemistry, Vol. 287, Issue 18, pp. 14456-66, (2012) (PubMed).

Freeman, Bowman, Zetter: "Regenerative protein thymosin beta-4 is a novel regulator of purinergic signaling." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 25, Issue 3, pp. 907-15, (2011) (PubMed).

Chentoufi, Kritzer, Tran, Dasgupta, Lim, Yu, Afifi, Jiang, Carpenter, Osorio, Hsiang, Nesburn, Wechsler, BenMohamed: "The herpes simplex virus 1 latency-associated transcript promotes functional exhaustion of virus-specific CD8+ T cells in latently infected trigeminal ganglia: a novel immune evasion mechanism." in: Journal of virology, Vol. 85, Issue 17, pp. 9127-38, (2011) (PubMed).

Surgucheva, Shestopalov, Surguchov: "Effect of gamma-synuclein silencing on apoptotic pathways in retinal ganglion cells." in: The Journal of biological chemistry, Vol. 283, Issue 52, pp. 36377-85, (2008) (PubMed).

Niculescu, Perrine, Miller, Ehrlich, Unterwald: "Trk: a neuromodulator of age-specific behavioral and neurochemical responses to cocaine in mice." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 28, Issue 5, pp. 1198-207, (2008) (PubMed).

Details zu P2RX4

Target: P2RX4 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 4 (P2RX4))

Andere Bezeichnung: P2RX4 / P2X4

Hintergrund: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of this gene has the lowest sensitivity for these antagonists. Multiple alternatively spliced transcript variants have been identified for this gene although their full-length natures have not been determined. [provided by RefSeq]Synonyms: ATP receptor, P2X purinoceptor 4, Purinergic receptor

Molekulargewicht: 43.4 kDa (NP_002551.2)

Gen-ID: 5025

NCBI Accession: NP_002551

UniProt: Q99571

Pathways: Synaptic Membrane