Galactosamine (N-Acetyl)-6-Sulfate Sulfatase (GALNS) Antikörper

Antigen: Galactosamine (N-Acetyl)-6-Sulfate Sulfatase (GALNS)

Synonyme: GAS, MPS4A, FLJ17434, FLJ42844, FLJ98217, GALNAC6S, FLJ00319, mFLJ00319, Galns, GALNS

Klonalität: Polyklonal

Wirt: Ziege

Reaktivität: Human

Applikation: Western Blot (WB)

Produktnummer: ABIN374878

Produktbeschreibung

Produktmerkmale: Synonyms: N-acetylgalactosamine-6-sulfatase, EC=3.1.6.4, N-acetylgalactosamine-6-sulfate sulfatase,Galactose-6-sulfate sulfatase, GalNAc6S sulfatase, Chondroitinsulfatase, Chondroitinase

Weitere Bezeichnung: GALNS

Swiss-Prot: P34059

Immunogen: Peptide from the internal region of the protein sequence according to NP_000503. 1Genename: GALNSAA Sequence: C-TTHNLEDHTKLP

Kreuzreaktivität: Human

Beschreibung: GALNS (N-acetylgalactosamine-6-sulfatase) is a lysosomal exohydrolase which catalyzesthe hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units ofchondroitin sulfate and of the D-galactose 6-sulfate units of keratan sulfate. Deficienciesof this enzyme lead to Morquio A syndrome, a lysosomal storage disorder.

Spezifität: This antibody detects GALNS. Species Reactivity: Tested: Human

Anwendungen

Applikationshinweise: Peptide ELISA: limit dilution 1: 64000. Western blot: 0.01-0.03µg/ml. Approx 60kDa band observed in Human Bone Marrow andPlacenta lysates (calculated MW of 58.0kDa according to NP_000503.1). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Konzentration: 0.5 mg/ml

Reinigung: Aff - Purified

Buffer: Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin

Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing. Shelf life: one year from despatch.

Forschungsgebiet: Proteolyse / Ubiquitin, Extrazelluläre Matrix, Organelle

Beschränkungen: Nur für Forschungszwecke einsetzbar