SECISBP2 Antikörper (Internal Region)
Kurzübersicht für SECISBP2 Antikörper (Internal Region) (ABIN374739)
Target
Alle SECISBP2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Internal Region
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Sequenz
- C-KERQERKQRL QEN
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Spezifität
- This antibody recognizes SBP2.
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Kreuzreaktivität (Details)
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Species reactivity (expected):Canine, Pig, Cow.
Species reactivity (tested):Human. -
Aufreinigung
- Affinity Chromatpography
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Immunogen
- Peptide with sequence from the internal region of the protein sequence according to NP_076982.3.
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Applikationshinweise
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Peptide ELISA: 1/64000. Western Blot: 0.1 - 0.3 μg/mL. Immunohistochemistry on paraffin sections: 3 μg/mL. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide and 0.5 % BSA
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- SECISBP2 (SECIS Binding Protein 2 (SECISBP2))
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Andere Bezeichnung
- SECISBP2
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Hintergrund
- SECISBP2 is an RNA binding protein that interacts with the Sec insertion sequence (SECIS) element in selenoprotein mRNAs. The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. Mutations in the SECISBP2 gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism.Synonyms: SBP2, SECIS-binding protein 2, Selenocysteine insertion sequence-binding protein 2
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Gen-ID
- 79048
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NCBI Accession
- NP_076982
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UniProt
- Q96T21
Target
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