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Antikörper
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anti-Cholinergic Receptor, Muscarinic 1 (CHRM1) Antikörper
Cholinergic Receptor, Muscarinic 1 (CHRM1) Antikörper
| Antigen |
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| Synonyme |
M1, HM1, M1R, MGC30125, Chrm-1, mAChR, CHRM1, DKFZp459P0517 |
| Klonalität |
Polyklonal |
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Wirt
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Reaktivität
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Applikation
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| Produktnummer |
ABIN374726 |
| Menge |
0.1 mg (0.5 mg/ml) |
| Preis |
250,00 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Produktmerkmale
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Synonyms: CHRM1, mAChR M1, mAChR-M1
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Weitere Bezeichnung
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Muscarinic acetylcholine receptor M1
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Swiss-Prot
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P11229
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Immunogen
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Peptide with sequence C-DKRRWRKIPKRPGSVH, from the C Terminus of the proteinsequence
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Kreuzreaktivität
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Hund, Human, Maus, Ratte (Rattus)
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Beschreibung
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The muscarinic cholinergic receptors belong to a larger family of G protein-coupledreceptors. The functional diversity of these receptors is defined by the binding ofacetylcholine and includes cellular responses such as adenylate cyclase inhibition,phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptorsinfluence many effects of acetylcholine in the central and peripheral nervous system. Themuscarinic cholinergic receptor 1 is involved in mediation of vagally-inducedbronchoconstriction and in the acid secretion of the gastrointestinal tract. Muscarinicreceptors are so called as they are more sensitive to the effects of the alkaloid muscarine,rather than nicotine.
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Spezifität
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This antibody reacts to M1 mAChR / CHRM1. Species Reactivity: Tested: Human. Expected from sequence similarity: Mouse, Rat, Canine.
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Applikationshinweise
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Peptide ELISA: 1/16000. Western Blot: 1 - 3 µg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Konzentration
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0.5 mg/ml
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Reinigung
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Aff - Purified
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Buffer
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Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
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Lagerung
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Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Forschungsgebiet
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Neurotransmitter , Hormone, Rezeptoren
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "Cholinergic Receptor, Muscarinic 1 (CHRM1)", Typ "Antikörper" finden